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The Medicines and Healthcare products Regulatory Agency (MHRA) has approved these medications following rigorous clinical trials demonstrating their efficacy in glycaemic control, with some agents (liraglutide, dulaglutide, and semaglutide) also showing cardiovascular benefits in specific populations

The Problems with Current GLP-1 Guidelines Traditional medicine waits to prescribe GLP-1 medications until a patients BMI hits 30 (obesity) or 27 with at least one weight-related health condition, such as high blood pressure or high cholesterol

If the target protein is close to 50kDa, use a light chain specific secondary

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