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Patients with a history of diabetic retinopathy should be monitored for progression of diabetic retinopathy

The free radicals superoxide (O 2 - ) and hydroxyl radical ( OH) are partial reduction byproducts of the mitochondrial respiration process, created by the partial reduction of oxygen, together with hydrogen peroxide (H 2 O 2 )

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Elevated blood TMAO levels cause an imbalance in cholesterol homeostasis which leads to influenced macrophages, which in turn causes foam cell development and atherosclerotic plaques [68, 69, 71]