Long-Term Effects of GLP-1 The question that many people would pose is: What are the negative side effects of GLP-1 in the long-term
Recent research comparing gastroparesis risk across weight loss modalities found semaglutide users without diabetes had higher gastroparesis incidence compared to those using other weight loss medications or undergoing bariatric surgery
The notoriety of the GLP-1s skyrocketed when nearly every media outlet, as well as non-health care influencers, created an enormous buzz around their weight-loss benefits, specifically for semaglutide and tirzepatide
For BMI 40+, or BMI 35+ with diabetes/sleep apnea, surgery generally produces more durable results
These reward phases are also linked since consummatory signals will depend on anticipated benefits (Kroemer & Small, 2016)
This requires collaborative efforts from policymakers, healthcare providers, pharmaceutical manufacturers, and PBMs themselves