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This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

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So, Im excited that retatrutide could be an option for our non-responders with obesity, Low Wang said

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This may translate to 2-4 kg of fat loss over a 12-16 week protocol, with significant individual variation based on adherence and individual factors