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The presence of TG enhances the influx and accumulation of LDL in the tunica intima, where it is oxidized by ROS, and picked up by macrophages via scavenger receptor (SR) CD36 to produce foam cells [169,170,171]

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The citric acid and ascorbic acid (vitamin C) in most formulations accelerate oxidation at temperatures above 8C, breaking down methionine into homocysteine

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