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SGLT2 Inhibitors: From Molecular Mechanisms to Clinical Outcomes in Cardiology and Diabetology

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doi:10.1186/s12916-016-0735-y

This imbalance leads to a decrease in the expression of AMPK downstream genes, including PGC1- and FOXO, ultimately resulting in the downregulation of 4E-BP and contributing to muscular laminopathy 8

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