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Peltek O, Kopoleva EA, Zyuzin MV

A single night of sleep deprivation increases ghrelin levels and feelings of hunger in normal-weight healthy men

Lower-dose maintenance and full discontinuation produce different outcomes

Both sensitivity analysis (Figure S2) and trim-and-fill procedure ( p = 0.504) showed no obvious low-quality trial

Patients who microdose successfully typically spend 812 weeks in the titration phase, reaching therapeutic doses between 0.52.4 mg weekly depending on their response profile

L-arginine serves as a substrate for arginase enzymes involved in polyamine synthesis, supporting cellular proliferation and tissue repair mechanisms