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Elevated levels of oxidative stress markers have been consistently reported in ME/CFS, including malondialdehyde (MDA), isoprostanes, 8-OH-deoxyguanosine, 2,3 diphosphoglyceric acid, thiobutyric acid, and protein carbonyls

Most patients see them resolve or significantly reduce as the body adjusts to the medication and the right food choices speed that adjustment

Levels of this protective antioxidant enzyme decrease as we age, but also when the body is faced with an increased burden of toxins, or when there are nutrient insufficiencies

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Restoring NAD+ removes this bottleneck