One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12
However, what's best for you will depend on the reason you have a deficiency and should be decided with your GP
In my own practice, especially if an older person has risk factors for vitamin B12 deficiency, I consider a vitamin B12 level of 200-400 pg/mL borderline, and I usually order a methylmalonic acid level as a follow-up
As a key beneficial genus within the gut microbiota, Bifidobacterium contributes to gut homeostasis through the secretion of SCFAs and suppression of pathogenic bacterial proliferation [37, 38]
Furthermore, this study was conducted during the initial stages of the SARS-CoV-2 pandemic
Even though they can be beneficial for your personalized weight loss program, receiving an injection in and by itself will not yield significant weight loss