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Moreover, KO mice for liver IGF-1 gene developed muscle insulin resistance (it is important to mention that skeletal muscle myocytes express high number of IGF-1R), showing an increase in insulin concentrations and a substantial decrease in the insulin-induced autophosphorylation of the insulin receptor and IRS in skeletal muscle (being normal in liver and white adipose tissue)

Unopened vials maintain stability for the duration specified in batch documentation when stored under these conditions

The gauge is lower (thicker needle) to help with a smooth injection into dense muscle tissue, and the length is significantly longer to ensure proper depth

Sanger, Queen Mary University of London, United Kingdom Updates Copyright 2020 Van den Houte, Scarpellini, Verbeure, Mori, Schol, Masuy, Carbone and Tack

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