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Topiramate primarily influences appetite through neurological pathways, while Semaglutide (Ozempic) modulates hunger and satiety via hormonal GLP-1 pathways and slows gastric emptying

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Because some of the anti-inflammatory action works independently of weight , even very small doses what clinicians call microdosing can calm the inflammatory signaling

Body weights were matched between groups at the start of liraglutide/saline treatment

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