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PMID 15463873

Concurrently, Ca 2+ overload activates calcium-dependent proteases (e.g., calpain) and phospholipases (e.g., Phospholipase A2 (PLA2)), which degrade cytoskeletal proteins (e.g., actin, tubulin) and membrane phospholipids, ultimately resulting in plasma membrane rupture [175]

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The complete set of differentially expressed proteins and their functions is summarized in Table 3A