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Clinical pharmacology of dipeptidyl peptidase 4 inhibitors indicated for the treatment of type 2 diabetes mellitus

10.1139/apnm-2020-0005 Appl

Unexpectedly, targeting ACLY (SB-204990), Acetyl-CoA Carboxylase 1 (ACC1, TOFA), FASN (TVB3166), FAO (etomoxir), LD biogenesis (Diacylglycerol Acyltransferase 1 and 2, DGAT1 and DGAT2, inhibitors) or lipid mobilization from LD (Adipose Triglyceride Lipase, ATGL, inhibitor, ATGListatin) showed no significant difference between 67NR and 4T1 cells (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Pham N.T.N., Huynh C.T.N., Nguyen A.T.T., Ho C.Q., Duong L.M., Bui D.T., Nguyen H.H