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By competitively binding FOXO4, it prevents FOXO4 from sequestering p53, thereby restoring the cells intrinsic apoptotic signaling capacity

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Aging Cell 24 , e70047 (2025)

Oral capsules: maximum 500 micrograms (0.5 milligrams)/day/2 times a day

It is not for human consumption or for use in diagnostic or therapeutic procedures

The trial protocol was approved by the Madrid Region Clinical Research Ethics Committee ( Comit tico de Investigacin Clnica Regional de la Comunidad de Madrid ) on February 8 th 2011, and has been registered with ClinicalTrials.gov number NCT 01476007, and under EUDRACT number 2010-024129-20 [Oral Versus Intramuscular Cobalamin to treat Cobalamin Deficiency: Noninferiority randomised controlled trial, pragmatic and multi-center in the primary healthcare setting (OB12 project)]