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However, the pathological function of OLFM4 in tumorigenesis including GC development remains to be clarified, especially regarding, (1) upstream signals and mechanisms through which OLFM4 expression and secretion are induced

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The key insulinotropic actions of GLP-1 via the class B1 G-protein-coupled receptor (GPCR) are exerted by cyclic adenosine monophosphate (cAMP) formation, which, in conjunction with increased Ca 2+ levels, promotes exocytosis of insulin-containing vesicles [39]

However, variability in GI physiology and safety constraints limit universal success

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Elucidating how SQOR expression is regulated during spermatogenesis is therefore of great importance for understanding certain male infertility conditions