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This review proposes a unified gut-centric hypothesis that intestinal barrier integrity, microbial homeostasis, and mucosal immune balance collectively determine the hosts resilience to viral invasion and inflammation
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The PPAR sensitizers were reported to improve the hepatic histologic findings of ballooning, lobular inflammation, and steatosis in a meta-analysis that compared the use of Thiazolidinediones to placebo in 334 individuals, but no significant improvement of fibrosis was detected