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Neuroprotection Neurodegenerative disorders encompass a collection of chronic progressive conditions that predominantly impact the structure and function of the central nervous system, with prevalent examples being Alzheimers disease, Parkinsons disease, Huntingtons disease, and amyotrophic lateral sclerosis [121]

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Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease