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The non-accidental ingestion of a very high dose of lipoic acid led to multi-organ failure and subsequent death of an adolescent girl (117)

August 2025: Recent studies offer additional data that taking Zepbound increases someones chances of developing NAION (nonarteritic anterior ischemic optic neuropathy), a condition that causes permanent vision loss and blindness

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It influences upstream pathways but is not a pharmacological therapy