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10 These modifications aim to reduce metabolic risk factors and promote weight loss, decreasing fat accumulation in the liver by creating a negative energy balance and promoting lipolysis, ultimately reducing fibrosis

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These results demonstrate that microbial TyrA orthologs from clade I, which contain an acidic residue at the corresponding 222 position (Figure 2, Data S2), are arogenate-specific TyrA a enzymes

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doi: 10.1016/S0014-5793(02)02775-8 36 GabeMBNvan der VeldenWJCSmitFXGasbjergLSRosenkildeMM