Upon cellular fractionation, mutants exhibited a significant decrease in tGSH and GSH in the cytosolic fraction compared to controls, where most cellular GSH is located (Extended Data Fig
In addition, arginine-capped manganese silicate nanobubbles (AMSNs) are nano-iron inducers that accelerate the depletion of GSH and cause the inactivation of GPX4, thereby inducing ferroptosis in cancer cells [298]
Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site
It can reduce the S-adenosylmethionine (SAM) levels, increase S-adenosine homocysteine (SAH), and decrease the SAM/SAH ratio by downregulating SAH expression
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