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The following skin parameters were recorded: hydration (corneometer), TEWL (tewameter), desquamation (standard D-Squame disc), wrinkles (trained dermatologist grading scale and PRIMOS 3D imaging system), and elasticity (ballistometer) at 4, 8, and 12 weeks

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boulardii , as a non-pathogenic probiotic yeast, exhibits greater tolerance to gastric acid and bile, and shows promise in modulating intestinal microecology and supporting management of chronic liver diseases

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Both require the same injection technique and site rotation principles

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