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This depletion may lead to longer recovery times or a feeling of fatigue

To counteract the toxicity of ROS, the body depends on a complex network of endogenous antioxidant systems, including SOD, glutathione (GSH), glutathione peroxidase (GPx), and heme oxygenase-1 (HO-1) (Jegadheeshwari et al., 2024), which collectively maintain cellular redox homeostasis (Meca et al., 2021)

Acetyl-L-Carnitine is generally considered safe for horses when fed at recommended levels

This improves blood flow to damaged tissues, delivering oxygen and nutrients that are essential for faster recovery and repair

A 2023 study published in Frontiers in Physiology found that endurance athletes following a low-carb high-fat (LCHF) diet for 9-36 months shifted their crossover point to above 80% of VO2max

However, this widely accepted assumption remains largely untested because of challenges in physiologically manipulating hepatic GSH levels during disease development