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Before reconstitution, the lyophilized powder is stable at room temperature, but keeping it in a cool, dark place is best practice

Dose titration was based on three preceding values of self-measured plasma glucose at the fasting state in all studies, although target ranges for self-measured plasma glucose were dissimilar

Another study demonstrated that caffeine reduces NLRP3 inflammasome activation by inducing autophagy in microglia [91], suggesting a potential mechanism for investigation in the context of mood disorders

doi:10.1016/j.eclinm.2020.100649 119

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Ann Pediatr Surg