Why Constipation Leads to Bleeding Constipation is one of the most frequently reported issues for those on GLP-1 programs
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The new Wegovy HD formulation (7.2 mg) showed approximately 21% average weight loss in the STEP UP trial, approaching the efficacy of injectable tirzepatide
Work closely with your prescribing physician before combining these approaches, and monitor blood glucose and ketone levels regularly

Protein supplementation combined with resistance training leads to greater preservation of lean mass and strength than training alone. Key point: With adequate protein intake and resistance training, patients can maintainand sometimes increasestrength during GLP-1 therapy despite overall weight loss. Recovery and micronutrients Adequate sleep, hydration, and correction of deficiencies (including vitamin D when present) further support muscle function and recovery. Bottom Line: GLP-1 Medications Improve Body Composition Not Muscle Wasting Semaglutide and tirzepatide do not inherently cause muscle wasting. Most weight lost is fat , and body composition improves. Muscle wasting is primarily a risk of undernutrition , not GLP-1 therapy itself. Protein + resistance training is the most effective strategy to preserve muscle. At Potere Health MD, GLP-1 and GIP therapy is paired with evidence-based nutrition and strength guidance so weight loss is healthier, stronger, and more sustainable