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Flavonoids provide a multi-target therapeutic strategy for bacterial pneumonia through various mechanisms, including direct antibacterial effects, suppression of bacterial pathogenicity, and regulation of the hosts immunological response to infection

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10 The first step in the biosynthesis of GSH is rate-limiting and is catalysed by glutamate-cysteine ligase (GCL)

As noted previously, increasing age is linked to reduced GSH levels (Drge, 2002a,b), which can be the result of extensive GSH oxidation and/or reduced pool of cell thiols, and cysteine (whey protein) administration enhances GSH levels and increases longevity (Bounous et al., 1989

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doi: 10.1369/0022155417751880 134 KarkhaneiB.Talebi GhaneE.MehriF