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Signs of an impending or active overdose include: [12] Extreme agitation Violent behavior Catatonic trance Coma Seizures Convulsions Severe hallucinations Dissociation Kidney failure Heart failure Psychosis Side-to-side eye movements (nystagmus) Loss of coordination This actually provides some support for the Nat Sherman theory of the terms origin, since Nat Sherman cigarettes were made (and most popular) in New York City

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