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The effective dose of silymarin and nicotine as well as duration of injection in the groups was determined according to previous studies [27,28,29,30]

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"Retail sales data are key to providing real-time information on the rapidly changing e-cigarette landscape, which is essential to reducing youth tobacco use." Citing the appeal of flavored e-cigarettes to children, the FDA announced in January 2020 that it would prohibit sales of sweet and fruit-flavored e-cigarette pre-filled pods, which led to the demise of big brands such as Juul and Vuse