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From heart disease to lung cancer, smoking is one of the leading causes of preventable death worldwide
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Despite this evidence, many American states tax non-combustible nicotine products at rates comparable to cigarettes
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This chapter also investigates various mechanisms of toxicity from the perspectives of pulmonary, inflammation, oxidative stress, DNA damage, apoptosis, transcriptome alterations, and epithelial-mesenchymal transition (EMT), all of which are directly linked to the effects of e-cigs
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