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Metabolic responses to carcinogenic toxicants exposure A significant reduction in exposure to carcinogens (including PAHs), free radicals (including ROS and RNS) and other oxidative stressors (such as aldehydes) should lead to a significant reduction in the activation of xenobiotic metabolism and oxidative stress responses

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In a 2022 report by the Bureau of Investigative Journalism, Sheffield expressed concerns about the tobacco industrys pattern of coercing under-funded organizations into supporting efforts that harm the well-being of Black communities

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