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Due to their presence, standard ISO 3308 smoke machines used to assess cigarette emissions strongly underestimate the actual exposure of smokers to TNCO and aldehydes (2022)

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Among studies including only two time points that addressed smoking progression, those that did not eliminate baseline ever smokers and used an alternate strategy for addressing reverse causation (e.g., statistical adjustment of baseline combustible tobacco use, elimination of baseline current combustible tobacco users without eliminating baseline past combustible tobacco users) were considered to provide less robust evidence of temporal precedence of an association of e-cigarette use with smoking progression (Etter, 2017)

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Academic Decline : Youth substance use is linked to poor grades, absenteeism, dropping out, and peer conflicts