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If rolling tobacco gets too dry, you end up with a harsh smoke that itches or even burns the throat and a too-quickly burning cigarette that turns into a cinder-filled mess

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NNK was also shown to inflict cellular damage in the pancreas (vacuolization, pyknotic nuclei, and edema) after a two week treatment period in rats

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The sense of unease heightens with the first appearance of the titular cigarette burns