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Control 11 , ii8ii13 (2002)

In contrast, the pooled OR for cohort studies was 1.145 (95% CI: 0.8421.557), and the confidence interval included 1, suggesting that the association was not statistically significant in longitudinal data

The interaction of AGEs with specific receptors, particularly the receptor for advanced glycation end-products (RAGE), triggers multiple intracellular signaling pathways, including NF-B, ERK1/2, p38, and MAPK, which in turn promote inflammatory responses and cellular stress (Yoshikawa et al., 2022

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