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Carrillos political life was over, although he had earned himself a place in public life as the man who had selflessly helped steer Spain from dictatorship to democracy

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With the development of delivery technologies and precision medicine, natural products are expected to advance from antioxidant/metabolic regulators to precision anticancer drugs. Despite the promising prospects, the field must overcome two major bottlenecks: 1) target specificity, by developing mitochondria-targeted delivery systems (e.g., TPP-modified nanoparticles) to avoid oxidative damage or energy interference in normal tissues by natural products

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