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In the UK between 1990 and 2010, predominant use of hand-rolled cigarettes among smokers older than 16 increased from two per cent to 23 per cent among women and from 18 per cent to 39 per cent among men

doi:10.1086/692318

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Symptoms of vaginal yeast infection Symptoms of vaginal yeast infection range from mild to moderate, and include: Severe itching and irritation in the vagina and surrounding area (vulva) Vulvar redness, which is less noticeable in darker-skinned women Thick, white-colored vaginal discharge, usually without a strong odor Burning sensation during urination and pain during intercourse General vaginal pain or discomfort In some cases, small cracks or fissures may appear in the skin of the vulva Diagnosing vaginal yeast infection Diagnosis of vaginal yeast infection is based on a description of symptoms and a clinical examination of the genital area