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PRSs were hence calculated with clumped SNPs for individuals with complete longitudinal neuroimaging, behaviour and genetic information ( n = 752) at a pre-defined set of P -value thresholds (i.e., 0.05, 0.1, 0.2, 0.3, 0.4, and 0.5)

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LIMITATIONS The sample size was quite small, and consisted of male Veterans

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Treating tobacco dependence should include both behavioral and pharmacologic interventions