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When issuing the MDOs, the FDA determined that the applications lacked sufficient evidence regarding the products toxicological profile to demonstrate that the marketing of the products met the public health standard required by law, according to an update from the FDA

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Overall, younger people were more likely to be dual users of snus and smoked tobacco, while older people were more likely to smoke than to use snus, according to the report in BMJ Open

The last domain consisted of three questions assessing staff level of comfort in discussing smoking with others

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