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During a 2005 episode of HBO's "Real Sports with Bryant Gumbel," the now-44-year-old NFL Hall of Famer said he used marijuana since entering the NFL in 1998

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Of the three oral agents, teriflunomide acts on the cytochrome P450 system by inhibiting CYP2C8 while inducing CYP1A2 (van der Weide et al., 2003)

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