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A striking observation is the apparent blockade of AHR in the model systems, whether it was driven by an allergic response to OVA or HDM

In other perspective, cigarette smoking has been found to negatively influence the endocrinal system, causing pituitary, thyroid, adrenal, testicular, and ovarian dysfunctions[]

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The dialogue not matching up to the scenes, and the scenes not always matching up to the timelines, forced you to drop assumptions and re-imagine how this was all going to end