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E-cigarettes affect digestion through: Rapid nicotine delivery to the bloodstream Higher nicotine concentrations in some products (up to 50mg/mL) Propylene glycol and vegetable glycerin, which may affect gut function Flavorings and additives with potential digestive effects These factors can trigger or worsen IBS symptoms in some users, including alternating constipation and diarrhea

In many e-cigarettes, the wick is in constant contact with extra e-liquid, so any vaporized e-liquid is immediately replaced

Public health groups are urging the Office of Management and Budget to act quickly and expedite the review so the final regulations could be issued by the end of the year

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