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More generally, as these are all observational studies, causality cannot be established, and there may be unaccounted-for confounding

Can occasional pipe smoking really be that harmful

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Cultural references [edit] Holders can be seen in period films like Titanic , and in films of the 1950s and 1960s

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Numerous other studies, such as the Albany Cardiovascular Health Center Study, the Chicago Peoples Gas Company Study, the Chicago Western Electric Company Study, and the Tecumseh Study, also substantiate a higher mortality rate for cigarette smokers than non-smokers