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Respiratory diseases are among the costliest preventable diseases caused by smoking

The authors minimized the search bias by developing search questions and literatures eligibility criteria (both inclusion and exclusion) based on the Population, Intervention, Comparison, Outcome, and Study (PICOS) framework (38)

Because it creates that rewarding effect, it can encourage repeated and, in some cases, abusive use of the drug

[48] Some people use e-cigarettes while continuing to smoke conventional cigarettes(dual use), for example during quit attempts or in situations where smoking is restricted

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Patches come in three strengths, and starting with the lowest dose that suppresses withdrawal symptoms is recommended