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Association between Cigarette Smoking and Mutation of the p53 Gene in Squamous-Cell Carcinoma of the Head and Neck Published March 16, 1995 N Engl J Med 1995;332:712-717 DOI: 10.1056/NEJM199503163321104 Abstract Background Although epidemiologic studies have long associated tobacco and alcohol use with the development of squamous-cell carcinoma of the head and neck, the molecular targets of these carcinogens have yet to be identified

Luxury vehicles with advanced infotainment systems usually cost more

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Here are some of the things we considered during our testing: Do the promised flavor notes come through

Others believe that any small infraction could earn you years behind bars