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The tobacco supply chain is made up of many players, from farmers to processors to retailers, but four large international corporations drive the industry: Philip Morris International, British American Tobacco, Japan Tobacco International and Imperial Brands.* They and their subsidiaries make up Big Tobacco, and are primarily responsible for perpetuating the worldwide tobacco epidemic

It was the worst I had ever felt in my life

JAMA 2021;325:26579

ISBN 84-933589-0-8

, nicotine, the main addictive chemical in tobacco smoke, is essential to continue and compulsive tobacco use

Lawmakers focused on the age of access among other anti-smoking efforts as a way to reduce tobacco access in schools, as 18-20 year-olds still in school or involved in activities after graduation could provide underage students with tobacco products