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Its immediate subjective effects, though they vary widely by dose, can include feelings of detachment from reality, distorted perceptions of one's body, an overwhelming desire to disrobe and hostile behavior

The agency concluded that the products have different characteristics than the predicate products, or that the four products have changed in composition from their previous versions, the FDA said in a press release

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public from the harmful effects of tobacco use. FDA said a company that wants to claim a product is safer than other tobacco products needs to ask the FDA and submit proof of its claim

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