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CSC increased VEGF and HIF-1 expression over a time course similar to that of the inflammatory cytokines, with maximal VEGF and HIF-1 mRNA levels being approximately two-fold (VEGF) and nine-fold (HIF-1) higher than those of the controls by 24 h (Fig

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For patients who smoke who are in the contemplation stage, the primary task is to increase their motivation: Ask patients why they want to quit

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