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People exposed to secondhand smoke early in life may experience health problems even sooner if they start smoking themselves, because early exposure can weaken their lungs and heart

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If you use opioid medications or illicit opioids, tell your provider before starting treatment

The spectrum of the recent research encourages the experts in the field to approach the Clinical, Molecular and cytogenetic shades associated with the problem besides secondary factors like life style and environment

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Pharmacol Rev 2005;57:79-115