when was the last cigarette commercial on television U.S. commercial: Virginia Slims 1970 | December 31 -

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After 72 hours of exposure to the aerosols generated by heat-not-burn devices, both bronchial epithelial cells and smooth muscle cells suffered a loss of viability, and an increase in lactate dehydrogenase release, collagen I and fibronectin, with a detrimental effect on the mitochondrial respiration chain

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PMID 21612464