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Epidemiological studies that associated tobacco use with lung cancer1 favoured addressing the modification of cigarette design.2 Since 1950, cigarettes have reduced the nicotine and tar content, as well as the content of other tobacco constituents

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He directs the Annenberg Physician Training Program in Addictive Disease at Mt

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doi:10.1046/j.1365-2184.1999.3210063.x 40