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doi:10.1056/NEJMra025411

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The Science Behind It Nicotine, classified as a stimulant, directly affects the parasympathetic nervous system (PNS), which is the part of your nervous system responsible for "rest and digest" functions

Smoking also has an effect on insulin, making it more likely that youll develop insulin resistance

The result is excruciating pain that is extremely difficult to manage this is the dreaded dry socket

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