doi:10.1136/tobaccocontrol-2018-054315
however, the lower risk in Latinos and the higher risk in Native Hawaiians evidently cannot be explained using TNE as a measure of intensity
Historically, from the 1970s, the tobacco industry has conducted pharmacological studies on several nicotine analogs, to understand their pharmacological effects and determine their potential to replace nicotine in products and also to circumvent any foreseeable regulations on nicotine 14
Since the devices themselves are legal, authorities struggle to distinguish between legal, nicotine-free versions and illegal, nicotine-containing ones
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Regions with a higher prevalence of current smoking tended to have lower smoking quit rates and higher relapse rates